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KMID : 0043319970200060610
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Archives of Pharmacal Research
1997 Volume.20 No. 6 p.610 ~ p.619
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Synthesis of 1-(Heterocyclic Substituted Anilino)-9H-Thioxanthon-9-ones and Their Antitumor Activity
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Omar Mahmoud-T.
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Abstract
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Some new 9H-thioxanthen-9-one incorporated into heterocyclic systems such as pyridone 8, pyrazoline 9, pyranone 11, iminopyrane 12, furopyrimidine 17, imidazothiazole 19, thiazole 21, triazine 24 and other related compounds through a para imminophenyl grouping at position-1 of the thioxanthenone ring were synthesized and tested as antitumor agents against L1210 leukemia in mice. Some of the new compounds showed considerable antitumor activity.
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KEYWORD
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Pyranone, Furopyrimidine, Imidazothiazole, Triazine, Antitumor activity
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